The Dangers of Mixing Benadryl and Alcohol. Alcohol and Benadryl Interaction, Effects, Warning & Treatment.
Benadryl has additive effects with alcohol and other CNS depressants (hypnotics, sedatives, tranquilizers). While the drug is relatively safe, it should not be combined with alcohol. Both Benadryl and alcohol can cause drowsiness and sedation. When taken together, they can intensify these effects, leading to extreme side effects. Continue to read more about Benadryl and alcohol interaction, addiction signs, and treatment.