By We Level Up | Author Alex Evans, PharmD, MBA | Editorial Policy | Research Policy
OCD Medication
Intrusive thoughts and repetitive habits to relieve anxiety make living with Obsessive-Compulsive Disorder (OCD) difficult. Treatment for OCD may include medication, therapy, and lifestyle changes.
This page discusses OCD medication side effects. We will also search for the finest medications to treat OCD, intrusive thoughts, and anxiety. Understanding medication and its effects helps patients and doctors make informed decisions to increase well-being and overcome OCD.
At We Level Up Treatment Center, we provide caring and complete OCD medication treatment options. Our goal is to help relieve the troubling symptoms of Obsessive-Compulsive Disorder.
Medications for OCD
Here is a list of common medications used for Obsessive-Compulsive Disorder (OCD):
OCD Medication List:
| Medication Type | Examples |
|---|---|
| SSRIs | Fluoxetine (Prozac), Sertraline (Zoloft), Paroxetine (Paxil), and more |
| SNRIs | Venlafaxine (Effexor), Duloxetine (Cymbalta) |
| Tricyclic Antidepressants | Clomipramine (Anafranil) |
| Atypical Antidepressants | Bupropion (Wellbutrin) |
| Antipsychotic Medications | Aripiprazole (Abilify), Risperidone (Risperdal), Quetiapine (Seroquel) |
| Anti-Anxiety Medications | Benzodiazepines (e.g., Clonazepam, Lorazepam) |
| Augmentation Agents | Lamotrigine (Lamictal), Buspirone (Buspar) |
| Experimental and Off-Label Medications | N-acetylcysteine, Memantine |
Side Effects of Medication for OCD
Like any other medicine, OCD medicine can have side effects. These side effects of OCD medications can differ depending on the drug type, how the person reacts to it, and how much is given. It’s important to remember that not everyone will have these side effects. Some people may only have mild or short-term effects. Here are some of the most common side effects of OCD medications:

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- Nausea and upset stomach: Many medicines can cause stomach pain. This can lead to nausea, vomiting, or an upset stomach.
- Drowsiness or tiredness: Some OCD medicines, especially those that change serotonin levels, can make you sleepy or tired.
- Sleep Problems or Insomnia: Some medicines can make it hard to fall asleep or stay asleep in a restful way.
- Dry Mouth: A dry mouth is a common side effect, especially of medicines that affect neurotransmitters.
- Headache: As the body adapts to the medicine, headaches can happen. They usually only last a short time, but they can be painful.
- Dizziness or Lightheadedness: Changing positions quickly can make you feel dizzy or lightheaded.
- Sexual Dysfunction: Some OCD medicines, especially selective serotonin reuptake inhibitors (SSRIs), can affect sexual desire, arousal, and effectiveness.
- Weight changes: Some medicines can cause you to gain or lose weight, which can upset some people.
- Agitation or Restlessness: Sometimes, OCD medicines can make you agitated or restless.
- Sweating: One side effect for some people is more sweating, especially at night.
- Tremors: Some people may feel shaking in their hands or other body parts.
- Changes in Blood Pressure: Some medications can cause blood pressure to go up and down, which can have different effects.
- Digestion Problems: Besides feeling sick, some people may have constipation, diarrhea, or other digestive problems.
- Allergic Reactions: Allergic reactions are rare but can happen with any medicine. They can cause signs like a rash, itching, swelling, or trouble breathing.
- Mood changes: Sometimes, OCD medications can change your mood. This may cause more worry, irritability, or other feelings.
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Conquering OCD can feel isolating and arduous. Many individuals struggle to navigate this condition without support and frequently relapse in their efforts to manage symptoms.
Fortunately, We Level Up offers comprehensive therapy and treatment plans tailored for OCD. With our expertise, you can expect a more manageable journey towards recovery. Should you need guidance for rehab, our treatment advocates are available around the clock to assist you.
OCD Medication Statistics
Explore OCD medication statistics to understand how often people use these medications. Look at trends in prescriptions and the overall effects of these drugs on those with OCD. By examining these statistics, we aim to better understand the role in the comprehensive management of OCD.
1. Medication Usage
Recent studies show that 60% to 70% of people with OCD use medication for treatment. This underscores medication’s significant role in the multifaceted approach to managing OCD.
2. Primary Medication Class – SSRIs
Selective Serotonin Reuptake Inhibitors (SSRIs) are the most commonly prescribed class of medications for OCD. Statistics reveal that around 50% to 60% of OCD patients are prescribed SSRIs as a first-line pharmacological intervention.
3. Medication and Therapy Studies
Show that using medication along with cognitive-behavioral therapy (CBT) is the most effective way to treat OCD. Studies show that up to 70% of individuals experience noticeable improvements when medication and therapy are employed.
4. Dosage Adjustments
It is not uncommon for healthcare providers to adjust medication dosages to achieve optimal therapeutic effects. Statistics indicate that around 30% of patients may undergo dosage modifications during their treatment.
2.5 million
OCD affects 2.5 million adults or 1.2% of the U.S. population.
Source: National Institute on Mental Health
25%
The average age of onset is 19, with 25% of cases occurring by age 14. One-third of affected adults first experienced symptoms in childhood.
Source: ADAA
3x
Women are 3x more likely to be affected than men.
Source: ADAA
Top 5 OCD Medication Studies with Insights
Medications like SSRIs and clomipramine help reduce OCD symptoms, while antipsychotic augmentation may assist in resistant cases. Combined with therapy, these treatments offer the most effective path to lasting recovery.
How We Level Up Turns Research Into Real Recovery
Our team takes proven OCD studies and transforms them into personalized care. Combining evidence-based medication with expert therapy, we ensure research drives every step of your journey toward lasting recovery.
| Study | Treatment Implications | Insights for Patients |
|---|---|---|
| Treatment non-response in obsessive-compulsive disorder: methodological issues and treatment strategies Review Study | Non-response in OCD is associated with serious social disability; careful evaluation and combined approaches may improve outcomes | Patients should discuss potential side effects and monitoring with their doctor. |
| A double-blind comparison of venlafaxine and paroxetine in obsessive-compulsive disorder View Source | Venlafaxine can be an alternative therapy, but it is not superior to SSRIs | May be considered if SSRIs cause side effects like sexual dysfunction or insomnia |
| Antipsychotic augmentation in SRI-refractory obsessive-compulsive disorder Read Article | Antipsychotic augmentation may benefit patients who do not respond to SSRIs | Discuss risks and benefits of antipsychotic use; monitor for metabolic or movement-related side effects |
| Meta-analysis of the dose-response relationship of SSRIs in obsessive-compulsive disorder View Study | Higher SSRI doses may provide greater symptom reduction in OCD | Improvement may be gradual; patience and adherence are critical. |
| Selective serotonin reuptake inhibitors in the treatment of obsessive-compulsive disorder Read Review | Medication can be tailored based on side effect profile and patient preference | Patients may try different SSRIs if one is not well-tolerated or effective |
What This Means for Your Care at We Level Up
Across these studies, a consistent message emerges: programs combine these proven pharmacological strategies with personalized therapy, structured routines, and expert support to help you achieve meaningful and lasting recovery. Every medication plan is carefully designed. It is part of a complete treatment approach. This approach helps with both symptoms and underlying issues. Ready to turn evidence into action? Contact We Level Up Treatment Centers for a private, free assessment. We will create a personalized plan tailored to your needs, informed by research.
Risks of OCD Medications
OCD medications can help reduce the symptoms of Obsessive-Compulsive Disorder (OCD). However, like any medication, they may have risks and side effects. It’s important to comprehensively understand these risks before starting any medication. Here are some potential risks associated with OCD medications:

- Side Effects: Nausea, drowsiness, dry mouth, dizziness, and more.
- Aggravation of Symptoms: Initial worsening of OCD before improvement.
- Sexual Dysfunction: Impact on sexual desire and performance.
- Emotional Changes: Mood swings and increased anxiety.
- Withdrawal Symptoms: Discontinuation can lead to withdrawal effects.
- Interaction with Other Medications: Possible harmful interactions.
- Risk of Suicidality: Slight increase in risk, especially at the start.
- Allergic Reactions: Rare but possible allergic responses.
- Long-Term Effects: Potential effects on health over time.
- Individual Variation: Different responses for each person.
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Best Medication for Intrusive Thoughts of OCD
Finding the best medication for OCD intrusive thoughts can be different for each person. This is because people respond to medications in different ways. However, certain medications have been commonly prescribed and found effective for managing OCD symptoms, including intrusive thoughts. It’s crucial to consult a qualified healthcare professional before making any decisions about medication. Here are some medications that are often considered:
1. Selective Serotonin Reuptake Inhibitors (SSRIs)
SSRIs are typically the first-line medications for OCD. They work by increasing serotonin levels in the brain, which can help reduce intrusive thoughts and anxiety. Examples include Fluoxetine (Prozac), Sertraline (Zoloft), and Paroxetine (Paxil).
2. Clomipramine (Anafranil)
This is a tricyclic antidepressant. It is often seen as the best medicine for treating OCD, including unwanted thoughts. However, it may have more side effects compared to SSRIs.
3. Augmentation Agents
Sometimes, doctors add medications like Aripiprazole (Abilify) or Risperidone (Risperdal) to an SSRI. These are antipsychotic medications that can improve the effects of the SSRI. These can be particularly useful if intrusive thoughts are not responding well to SSRIs alone.
4. Combination Therapy
Sometimes, doctors may prescribe different medications. This helps target various aspects of OCD symptoms, like intrusive thoughts. A healthcare provider should closely monitor this.
5. Personalized Approach
Individual responses vary, and what works for one person might not work for another. Working closely with a healthcare provider to find the most effective medication while considering potential side effects is essential.
Remember that medication is usually just part of a comprehensive treatment plan for OCD. Therapy, particularly Cognitive Behavioral Therapy (CBT), is often recommended with medication to achieve the best results. The best medication for you should be chosen with help from a psychiatrist or a qualified mental health professional.
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7/365 Line (844) 597-1011Best Medication for Anxiety and OCD
People with anxiety and OCD (Obsessive-Compulsive Disorder) choose their medicine based on a few factors. These include the severity of their symptoms, their response to medications, and any potential side effects. For personalized advice, talk to a health expert. Still, some drugs are often thought of as ways to treat both anxiety and OCD:
1. Selective Serotonin Reuptake Inhibitors (SSRIs)
SSRIs are often prescribed as a first-line treatment for anxiety disorders and OCD. They work by increasing serotonin levels in the brain, which can help alleviate symptoms of both conditions. Examples include Fluoxetine (Prozac), Sertraline (Zoloft), and Escitalopram (Lexapro).
2. Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs)
SNRIs are another class of antidepressants that can effectively treat anxiety and OCD. Venlafaxine (Effexor) and Duloxetine (Cymbalta) are examples of SNRIs.
3. Tricyclic Antidepressants
Tricyclic antidepressants like Clomipramine (Anafranil) are sometimes used to target symptoms of both anxiety and OCD. However, they tend to have more potential side effects compared to newer medications.
4. Combination Therapy
In some cases, healthcare providers might prescribe a combination of medications to address anxiety and OCD symptoms. For instance, an SSRI could be combined with a low-dose antipsychotic like Aripiprazole (Abilify).
5. Benzodiazepines
These are not usually the first choice because they can cause dependence and withdrawal. However, short-term benzodiazepines like Clonazepam or Lorazepam may help with sudden anxiety symptoms. These are typically prescribed for a short duration and under close supervision.
6. Personalized Approach
Finding the best medication often involves a trial-and-error process, as individual responses can vary. What works for one person might not work for another.
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Fast-Acting OCD Medication
Right now, there is no medicine for OCD (Obsessive-Compulsive Disorder) that is labeled as “fast-acting.” This is different from some available pain relievers. It usually takes a while for the full effects of anti-OCD medication to kick in. Most antidepressants and selective serotonin reuptake inhibitors (SSRIs) for obsessive-compulsive disorder (OCD) take time to work. They usually need a few weeks to show their full effects.
Remember that getting well while being treated for OCD is a slow process. Treatments may not provide instantaneous relief like other treatments, but can relieve symptoms dramatically over time. Cognitive Behavioral Therapy (CBT) can help you learn to manage and cope with your OCD symptoms before the meds take effect.
Let’s say you’re seeking a way to deal with a sudden emotional crisis as soon as possible. In that case, it’s best to talk to a doctor. They can help you decide on treatment options. This may include counseling, short-term measures, or medication.
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OCD Treatment Medication
The main types of medications for treating Obsessive-Compulsive Disorder (OCD) are antidepressants. This includes selective serotonin reuptake inhibitors (SSRIs) and sometimes other medications. Medication is usually only one part of a complete treatment plan for OCD. This plan often includes therapy, like Cognitive Behavioral Therapy (CBT). Here are some commonly used OCD treatment medications:
- Antipsychotic Medications (used as augmenting agents):
- Aripiprazole (Abilify).
- Risperidone (Risperdal).
- Quetiapine (Seroquel).
- Anti-Anxiety Medications (for short-term relief):
- Benzodiazepines (e.g., Clonazepam, Lorazepam).
- Augmentation Agents (used in combination with antidepressants):
- Lamotrigine (Lamictal).
- Buspirone (Buspar).
- Atypical Antidepressant:
- Bupropion (Wellbutrin).
- Selective Serotonin Reuptake Inhibitors (SSRIs):
- Fluoxetine (Prozac).
- Sertraline (Zoloft).
- Paroxetine (Paxil).
- Fluvoxamine (Luvox).
- Escitalopram (Lexapro).
- Citalopram (Celexa).
- Tricyclic Antidepressant:
- Clomipramine (Anafranil) – Particularly effective for OCD, though it may have more side effects than SSRIs.
- Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs):
- Venlafaxine (Effexor).
- Duloxetine (Cymbalta).
OCD Treatment Without Medication
Obsessive-Compulsive Disorder (OCD) can be treated effectively through various approaches, even without medication. While medication is an option, therapy is often a central component of OCD treatment. Here are some non-medication treatment options for OCD:
1. Cognitive Behavioral Therapy (CBT)
CBT is the most widely recommended therapy for OCD. Exposure and Response Prevention (ERP) is a type of CBT. It slowly exposes a person to their obsessive thoughts. At the same time, it stops the related compulsive behaviors. Over time, this helps lower anxiety. It also weakens the connection between obsessions and the need to do rituals.
2. Mindfulness and Acceptance-Based Therapies
Mindfulness techniques help people notice their thoughts and feelings. They do this without trying to control or hide them. Acceptance and Commitment Therapy (ACT) is a mindfulness approach. It helps people accept difficult thoughts. At the same time, it encourages focusing on values and taking committed actions.
3. Behavioral Therapy
Apart from ERP, other behavioral strategies can help address specific behaviors associated with OCD. These might include habit reversal training or techniques to manage specific compulsions.
4. Support Groups
Support groups, whether in-person or online, help people with OCD connect. They can share experiences and learn from others facing similar challenges.
5. Psychoeducation
Learning about OCD, its mechanisms, and effective coping strategies can empower individuals to manage their symptoms better.
6. Lifestyle Changes
Regular exercise can boost mental health. Eating a healthy diet is important too. Getting enough sleep helps as well. Reducing stress can also improve symptoms.
7. Self-Help Books and Resources
Many self-help books, websites, and apps help people learn different OCD treatment methods.
8. Professional Guidance
It is important to talk to a trained therapist or psychologist who knows how to treat OCD. They can help create a treatment plan that fits your needs.
It’s essential to note that the effectiveness of treatment can vary based on individual factors. Many people with OCD do well with therapy alone. Some may also benefit from therapy and medication together. Working closely with a mental health professional is recommended to determine the most appropriate treatment plan.
If you need help with your OCD, check out the OCD medication programs at We Level Up Treatment Center. Our skilled team is here to support you on your path to better mental health.
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Popular OCD Medication FAQs
-
Is There Medication for OCD?
Yes, there are medications available for treating OCD (Obsessive-Compulsive Disorder).
-
What Does OCD Mean in Medical Terms?
In medical terms, “OCD” means Obsessive-Compulsive Disorder. This is a mental health condition. It is marked by recurring obsessions and compulsions. Obsessions are intrusive, unwanted thoughts. Compulsions are repetitive behaviors. People feel driven to perform these behaviors in response to their obsessions.
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What Is the Best Medication for OCD?
The best medication for OCD can vary for each individual. Commonly prescribed medications include selective serotonin reuptake inhibitors (SSRIs) like Fluoxetine (Prozac) and Sertraline (Zoloft), as well as Clomipramine (Anafranil), a tricyclic antidepressant. The most suitable medication depends on factors such as the individual’s specific symptoms, medical history, and response to treatment. Consulting a healthcare professional is essential to determine the best option for you.
-
Does OCD Medication Change Your Personality?
OCD medication usually does not change who you are. It helps reduce OCD symptoms and improve your life.
Watch 2 Insightful YouTube Videos That Explain OCD Clearly
Search We Level Up The Most Effective OCD Medication for Treatments & Recovery Resources
Resources
OCD Treatment – Comprehensive approaches to OCD beyond medication.
OCD Test – A screening tool for identifying symptoms.
Relationship OCD Guide – Focused resource on ROCD and its impact.
Sources
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[2] Obsessive-compulsive disorder. National Institute of Mental Health. https://www.nimh.nih.gov/health/topics/obsessive-compulsive-disorder-ocd/index.shtml. Accessed Sept. 3, 2019. Learn More: best medications for ocd
[3] Mental health medications. National Institute of Mental Health. https://www.nimh.nih.gov/health/topics/mental-health-medications/index.shtml#part_149856. Accessed Aug. 13, 2019. Learn More: ocd meaning medical
[4] AskMayoExpert. Obsessive-compulsive disorder (OCD). Mayo Clinic; 2019. Learn More: Types of OCD
[5] Depression basics. National Institute of Mental Health. https://www.nimh.nih.gov/health/publications/depression/index.shtml. Accessed Sept. 4, 2019. Learn More: ocd medical abbreviation
[6] Obsessive-compulsive disorder (OCD). Merck Manual Professional Version. https://www.merckmanuals.com/professional/psychiatric-disorders/obsessive-compulsive-and-related-disorders/obsessive-compulsive-disorder-ocd. Accessed Sept. 3, 2019. Learn More: fast-acting ocd medication
[7] Obsessive-compulsive disorder. National Alliance on Mental Illness. https://www.nami.org/Learn-More/Mental-Health-Conditions/Obsessive-compulsive-Disorder/Overview. Accessed Sept. 3, 2019. Learn More: What does ocd mean in medical terms
[8] Suicidality in children and adolescents being treated with antidepressant medications. U.S. Food and Drug Administration. https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/suicidality-children-and-adolescents-being-treated-antidepressant-medications. Accessed Aug. 13, 2019. Learn More: Types of OCD, ocd ruining relationship
[9] Obsessive-compulsive disorder. In: Diagnostic and Statistical Manual of Mental Disorders, DSM-5. 5th ed. American Psychiatric Association; 2013. https://dsm.psychiatryonline.org. Accessed Sept. 3, 2019. Learn More: Types of OCD, ocd and intimate relationships
[10] Coping with Stress – Centers for Disease Control and Prevention Learn More: Types of OCD, relationship ocd or wrong relationship


