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What to Know About Codeine Addiction and Withdrawal

Codeine is the most commonly taken opioid medication. It is at the center of the opioid addiction problem in the United States and thus is highly regulated. Codeine's main indications are pain and dry cough. Read more about codeine uses, effects, addiction, and rehab treatment.

By We Level Up | Author Alex Evans, PharmD, MBAEditorial Policy | Research Policy

Codeine is an opioid medication used to treat mild to moderate pain. It’s also found in some prescription cough syrups. While it can be effective when used as directed, there is a risk of dependence and addiction with codeine.

Long-term codeine use can lead to tolerance, meaning you need higher doses to get the same effects. If you suddenly stop taking codeine, you may experience withdrawal.

Codeine addiction can develop gradually. You may start taking more than prescribed to manage pain or simply to feel good. Being aware of the signs of codeine addiction and seeking professional help are important first steps. Treatment options are available to help you safely withdraw from codeine and overcome addiction.

Key Takeaways

  • Codeine is an addictive opioid medication that can lead to physical dependence and addiction, especially with prolonged use or misuse
  • Withdrawal symptoms such as anxiety, muscle aches, insomnia, and cravings can occur when stopping codeine use abruptly
  • Codeine overdose can be life-threatening, with symptoms including slow breathing, confusion, and loss of consciousness
  • Codeine lean, a mixture of codeine cough syrup and other ingredients, is a dangerous and illegal practice that can lead to serious health consequences

What is Codeine?

Codeine is an opioid medication used to treat mild to moderate pain. It’s also commonly found in some prescription cough syrups. When taken as prescribed, codeine is an effective option for pain and for cough. But, it can also produce feelings of relaxation and euphoria, which may lead to psychological dependence over time. Because of this, there is a risk of addiction and dependence, especially with prolonged use or misuse.

Also, abruptly stopping or significantly reducing codeine use can lead to withdrawal symptoms such as anxiety, restlessness, muscle aches, and gastrointestinal distress.

If you suspect codeine addiction in yourself or a loved one, talk to your healthcare provider. They can help determine the next best steps, including whether or not you need to gradually get off the medication and if you need help for either dependence or addiction.

How Long Does Codeine Stay in Your System?

Does codeine show up in a drug test? Yes. For most individuals, codeine can be seen in their urine for up to forty-eight hours after their previous drug use.

Codeine drugs, like other opioid medications, are included in the typical and most common drug panel.

For chronic codeine users, the drug can be detected through drug panels for up to one week or more.

What Does Codeine Look Like?

Codeine is available in different forms and dosages, so its appearance can vary depending on the product. Some common forms of codeine include tablets, capsules, and syrup. Promethazine codeine cough syrup is a liquid medication that is usually brown or purple and has a sweet taste. It may be packaged in a bottle or a small cup.

Close-up of codeine pills emphasizing their medical use and addiction risk

Why is Codeine Addictive?

All opioids, including codeine, are addictive. It binds to opioid receptors in your brain that relieve pain but also produce feelings of relaxation and euphoria. It affects the brain’s reward system by increasing dopamine levels, reinforcing drug-seeking behavior. 

Even when taken as prescribed, codeine can cause physical dependence over time. Over time, you may start to crave the drug and prioritize its use over other activities and responsibilities. It can develop gradually, and you might not realize you’ve become dependent until you try to stop taking the medication.

Certain factors can increase your risk of opioid use disorder (addiction), such as a personal or family history of substance abuse, mental health disorders, and chronic pain. Long-term codeine also increases your risk for addiction.

Codeine Cough Syrup Side Effects

Codeine cough syrup can be an effective cough treatment but can also cause several side effects. Some common side effects of codeine cough syrup include:

  • Drowsiness and Sedation: Codeine can cause drowsiness and sedation, impairing your ability to drive or operate machinery.
  • Dizziness: Cough syrup codeine can cause dizziness or lightheadedness, increasing the risk of falls.
  • Nausea and Vomiting: Codeine can cause stomach upset, nausea, and vomiting.
  • Constipation: Codeine for a cough can cause constipation by slowing bowel movement.
  • Respiratory Depression: Codeine can suppress breathing and can be especially dangerous for people with respiratory problems or taking other medications that can cause respiratory depression.
  • Codeine Allergy Reactions: Some people may experience allergic reactions to codeine for cough, including rash, itching, swelling, and difficulty breathing.
  • Dependence and Codeine Abuse: Codeine has a high potential for dependence and addiction, mainly when used for extended periods or in higher doses than recommended.

Codeine Lean

“Codeine lean” is a term commonly used to refer to a recreational drug mixture that contains codeine (an opiate) and a carbonated beverage, such as soda or energy drink, along with candy or other sweeteners. Is lean addictive? Yes! This mixture is often consumed in large quantities and can produce a sense of euphoria, relaxation, and drowsiness.

Lean addiction can be very hazardous and even deadly. Codeine is a highly addictive drug and can cause respiratory depression, coma, and death if taken in excessive amounts or mixed with other medicines, especially alcohol. Furthermore, guaifenesin codeine syrup for recreational purposes is illegal in many countries.

How addictive is lean? Codeine, the main ingredient in lean, is a highly addictive opiate that can cause physical dependence and withdrawal symptoms when used regularly or in high doses. Promethazine with codeine side effects can also cause drowsiness and other side effects, especially when combined with other drugs or alcohol. Mixing lean with other substances, such as alcohol, benzodiazepines, or other opiates, can increase the risk of respiratory depression, coma, and death.

If you or someone you’re concerned with is addicted to lean, seeking professional help from a healthcare provider or codeine addiction specialist is crucial.

Signs of Codeine Addiction

For codeine, the signs and symptoms of opioid use disorder include:

  • Developing problems with personal or professional relationships due to codeine use
  • Taking codeine in larger amounts or for a longer period than prescribed
  • Trying to cut back on codeine use but being unsuccessful
  • Having cravings for codeine
  • Using codeine in situations where it would be hazardous (ex. driving)
  • Not meeting family, work, or social responsibilities because of codeine use

Is Tylenol With Codeine Addictive?

Yes, Tylenol with codeine effects can be addictive due to its codeine content. Codeine is an opioid analgesic, which means it is a type of pain medication that works by binding to the brain’s opioid receptors and spinal cord to reduce pain sensations. Like other opioids, Tylenol codeine effects can cause physical dependence and addiction when used regularly or in high doses. Dependency occurs when the body adjusts to Tylenol and codeine and requires it to function normally. Despite the negative consequences, addiction to codeine Tylenol high is a chronic disease characterized by compulsive drug use.

Taking Tylenol with codeine for a short period and under the direction of a healthcare provider is generally safe. However, prolonged or unsupervised use of Tylenol with codeine can increase the risk of codeine addiction, overdose, and other health complications.

It is crucial to follow the prescribed dosage and not take more than the recommended amount. Suppose you or someone you’re concerned with is struggling with addiction to Tylenol with codeine high or other drugs. In that case, seeking professional help from a healthcare provider or addiction specialist is critical.

Acetaminophen Codeine 3

Acetaminophen codeine 3, also known as Tylenol with codeine 3, is a prescription medication that contains codeine (an opioid pain reliever) and acetaminophen (a non-opioid pain reliever). It is used for the treatment of moderate to severe pain.

Codeine functions by binding to opioid receptors in the brain and spinal cord, which reduces pain signals. On the other hand, acetaminophen works by inhibiting the release of prostaglandins, which are the primary cause of pain and inflammation in the body.

While acetaminophen codeine 3 can be an effective pain management medication when appropriately used, codeine is a highly addictive drug that can cause physical dependence and withdrawal symptoms when used regularly or in high doses. Acetaminophen can also be toxic to the liver if taken excessively or over a prolonged period.

Acetaminophen Codeine Side Effects

Some of the common side effects of side effects of Tylenol 3 with codeine include the following:

  • Drowsiness.
  • Dizziness.
  • Nausea and vomiting.
  • Constipation.
  • Dry mouth.
  • Blurred vision.
  • Headache.
  • Sweating.
  • Itching or rash.
Therapist counseling a patient on overcoming codeine addiction

In addition to these common Tylenol 3 codeine side effects, acetaminophen codeine 3 can also cause severe side effects in some cases, such as the following:

  • Respiratory depression. (slow breathing)
  • Hypotension. (low blood pressure)
  • Hepatotoxicity. (liver damage)

Codeine Guaifenesin Addiction

Codeine is an opioid pain reliever, and guaifenesin is an expectorant. Codeine guaifenesin 10-100 mg/5ml should only be used as prescribed by a healthcare provider for their intended purpose, which is to relieve cough and congestion caused by respiratory conditions. Using Codeine Guaifenesin recreationally, in more significant amounts or more frequently than prescribed, can lead to physical dependence, addiction, and other serious health consequences. Codeine guaifenesin can also interact with other medications or substances, such as alcohol, increasing the risk of adverse effects and overdose.

Suppose you or someone you’re concerned with is struggling with substance abuse or codeine guaifenesin high addiction. In that case, seeking professional help from a healthcare provider or addiction specialist is crucial. They can provide information on treatment options and support to help overcome codeine addiction.

Codeine vs Hydrocodone

Codeine and hydrocodone are both opioid pain medications and work in the same way. 

Hydrocodone is a semi-synthetic opioid. Codeine is a natural opioid derived from the opium poppy plant. Hydrocodone is generally more potent than codeine and often prescribed for moderate to severe pain. Codeine is typically used for mild to moderate pain and for cough.

Both medications carry risks of addiction, dependence, and withdrawal. It’s possible these risks are higher with hydrocodone since it is more potent. Both hydrocodone and codeine tablets are Schedule II medications. Codeine is also found in commonly prescribed cough syrups. In this case, codeine is typically in a lower drug schedule, meaning it is not as highly regulated as codeine or hydrocodone tablets.

Codeine Withdrawal Symptoms

When you stop taking codeine after prolonged use, you may experience withdrawal symptoms. These can range from mild to severe, depending on factors like the duration and amount of codeine used. 

Withdrawal typically begins within a few hours to a day after your last dose. Common withdrawal symptoms include:

  • Anxiety and restlessness
  • Muscle aches and pains
  • Sweating and chills
  • Runny nose and watery eyes
  • Nausea, vomiting, and diarrhea
  • Insomnia and disturbed sleep patterns
  • Intense cravings for codeine

Do not attempt to manage codeine withdrawal alone. Contact your healthcare provider for help. They can develop a personalized tapering schedule to gradually reduce your codeine intake, minimizing withdrawal severity. They may also recommend medications to alleviate specific symptoms. 

Codeine Overdose Symptoms

Codeine overdose can be life-threatening. Your risk for overdose is higher if you take more than the recommended dose or combine codeine with other substances like alcohol or benzodiazepines.

Common codeine overdose symptoms include:

  • Pinpoint pupils
  • Slow, shallow, or irregular breathing
  • Bluish lips or fingernails
  • Cold, clammy skin
  • Confusion or disorientation
  • Extreme drowsiness or loss of consciousness
  • Weak pulse
  • Low blood pressure
  • Seizures

If you suspect a codeine overdose, call 911 immediately. Don’t wait for symptoms to worsen. Administer Narcan (naloxone) if you have it. Emergency responders may also administer naloxone. The person will then need to be taken to the hospital for supportive care.

To prevent codeine overdose, always follow prescribed dosages. Don’t mix codeine with other medications unless your healthcare provider says it’s OK. Keep codeine out of reach of children and properly dispose of unused medication.

Naloxone (Narcan) is a medication that can reverse an opioid overdose and save a person’s life. It functions by blocking the effects of opioids on the brain and restoring normal breathing. If you are concerned about opioid overdose or want naloxone, you must talk to your healthcare provider or pharmacist. Many states have standing orders that allow pharmacists to dispense naloxone without a prescription.

Codeine Drug Facts

Generic Name: Codeine [ KOE-deen ]
Drug Classes: Antitussives, Opioids (narcotic analgesics)
Codeine Drug Schedule: In the United States, codeine is a prescription medication classified as a Schedule II controlled drug.
Codeine in Spanish: “Codeina” or “Codeina 3”
Codeine Cough Syrup Brands: Brand names Phenergan with codeine (promethazine and codeine) and Tuzistra (chlorpheniramine and codeine) are some samples of codeine-containing drugs used to ease coughs and cold symptoms, such as sneezing, runny or stuffy nose, and other allergy signs.

Other Drugs With Codeine:

  • Fioricet with codeine is a combination drug product to treat a tension headache.
  • Codeine sulfate is an opioid analgesic for alleviating mild to moderately severe pain where an opioid anesthetic is suitable.
  • Robitussin Ac (codeine-guaifenesin) combines an expectorant and a narcotic to treat cough and reduce chest congestion caused by upper respiratory infections or the common cold. People often call it “Robitussin codeine” or Robitussin with codeine.
  • Acetaminophen and codeine (Tylenol-codeine phosphate) is a combination drug containing codeine and acetaminophen to relieve pain. It is also known as “APAP/codeine” or “APAP codeine” in the medical field.
    • Numerous pharmacists still use this abbreviation when writing patient-specific prescription labels. Patients may need to understand that APAP means acetaminophen.
  • Promethazine with codeine syrup relieves cough, runny or stuffy nose, sneezing, or other symptoms induced by allergies or the common cold. Promethazine is an antihistamine. It prevents the effects of a substance called histamine, produced by the body.

Can You Snort Codeine?

Technically, it is possible to snort codeine, but it is not a recommended method of administration. Codeine is designed to be taken orally as a pill, syrup, or tablet, and snorting it can increase the risk of codeine addiction and overdose. Snorting codeine can irritate the nasal passages, cause nosebleeds, and damage the delicate tissues inside the nose.

Snorting codeine can lead to a more rapid onset of effects and a higher concentration of the drug in the bloodstream, which can increase the risk of overdose and other adverse effects.

How Addictive is Codeine?

Codeine as a drug can be habit-forming. Addiction to codeine leads not only to psychological dependency but also to physical manifestations through unwanted withdrawals.

The Codeine drug class is opioid. Opioid common drugs such as codeine and morphine are highly addictive. Is codeine a drug? Yes. Unfortunately, codeine narcotics are often misused for the euphoria they produce, and they’re prevalent in nightclubs and even among college students.

It is critical to use the drug codeine only as advised by a healthcare provider and to avoid methods of liquid codeine administration that are not recommended or approved. Moreover, it is crucial to store codeine medicine and other medications safely and securely out of reach of children and others who might misuse them.

Following your doctor’s recommended dosage for codeine can save your life. But for someone who may have been addicted to codeine drugs already, seeking professional help from an accredited rehab treatment center can help avoid the dangers of opioid withdrawal and overdose.

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Codeine Addiction Statistics

Prolonged use of codeine can lead to addiction, tolerance, and dependence, which can have serious health consequences. However, many users find ways to get addicted to the drug recreationally and fast. Lean drink, also known as Purple drank, Sizzurp, or Dirty Sprite, is a recreational drug concoction that originated in Southern hip-hop culture. It generally consists of prescription-strength cough syrup containing promethazine with codeine dosage, mixed with soda (often Sprite) and sometimes candy, such as Jolly Ranchers, and ice.

The codeine in the cough syrup is a powerful opioid pain medication that can cause feelings of euphoria and relaxation. At the same time, promethazine is an antihistamine that can enhance the effects of codeine. The soda and candy are added to improve the taste and mask the bitter flavor of the cough syrup.

However, the lean drink is a dangerous and potentially deadly drug. The combination of codeine and promethazine can cause respiratory depression, leading to coma or death. The high doses of codeine in cough syrup can also lead to addiction, tolerance, and dependence. Lean drinking is illegal and can have serious health consequences. If you or someone you’re concerned with is struggling with codeine addiction, seeking professional help and support is crucial.

In 2018, 1,029 party attendees (ages 18–40) were surveyed in New York City utilizing time-space sampling. Prevalence and correlates of Lean drinking were estimated. This survey is available from the published research in NCBI (National Center for Biotechnology Information). [2]


15.5%

An estimated 15.5% of attendees have used Lean, a codeine-contained drink, and 3.4% have used it in the past year.

Source: NCBI

14.2%

Only an estimated 0.2% have used it in the past month, but 14.2% would use it next month if offered by a friend.

Source: NCBI

75.4%

Three-quarters (75.4%) of users believed Lean contained codeine, and 32.4% thought it always or usually had codeine.

Source: NCBI


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The Effects of Guaifenesin-Codeine

Codeine and guaifenesin are commonly used together to relieve coughs associated with respiratory tract infections or allergies. While these medications are generally safe when used as directed, they can cause side effects in some people.

middle-aged man sitting on a couch looks fatigued holding a bottle of prescription codeine cough syrup

Some of the common codeine guaifenesin side effects include the following:

  • Drowsiness and fatigue.
  • Nausea and vomiting.
  • Constipation or diarrhea.
  • Dizziness or lightheadedness.
  • Headache.
  • Dry mouth.
  • Sweating.
  • Rash or itching.

In rare cases, codeine can cause more severe side effects, such as respiratory depression (slowed breathing) or allergic reactions.

If you encounter any of the following symptoms after taking codeine and guaifenesin, seek medical attention right away:

  • Difficulty breathing.
  • Chest pain or tightness.
  • Severe drowsiness or confusion.
  • Seizures.
  • Hallucinations.
  • Fainting or loss of consciousness.

Other Acetaminophen-Codeine Effects

Codeine acetaminophen is often used to relieve pain. While acetaminophen/codeine is generally safe when used as directed, it can cause side effects in some people. Often, many people call it “acetami/codein.” Long-term use of codeine and acetaminophen can also lead to dependence, addiction, or liver damage. It’s crucial always to follow your doctor’s instructions when taking any medication and to report any side effects you experience to your healthcare provider.

In rare cases, codeine and acetaminophen can cause more severe side effects, such as respiratory depression (slowed breathing) or allergic reactions. If you undergo any of the following symptoms after taking codeine and acetaminophen, seek medical attention right away:

  • Chest discomfort or tightness.
  • Problem breathing.
  • Severe tiredness.
  • Loss of consciousness.
  • Seizures.
  • Hallucinations.

Acetaminophen / Codeine Side Effects

Some of the common side effects of codeine and acetaminophen (acetaminophen codeine 3 efectos secundarios) include the following:

  • Dizziness or sleepiness.
  • Nausea.
  • Stomach discomfort and constipation.
  • Dry mouth.
  • Headache.
  • Sweating.
  • Allergic codeine reactions, such as rashes.

Side Effects of Tylenol Codeine

Tylenol with codeine #3 is a prescription medication containing codeine and acetaminophen. This medication relieves mild-to-moderate pain, such as pain from dental work, surgery, or injury. While Tylenol with codeine #3 is generally safe when used as directed, it can cause side effects in some people. One common side effect of Tylenol with codeine #3 is drowsiness. Other Tylenol with codeine 3 side effects are the same as the side effects of codeine acetaminophen and guaifenesin codeine medicines.

In rare cases, Tylenol with codeine #3 can cause more severe side effects, such as respiratory depression (slowed breathing) or allergy to codeine. Long-term use of Tylenol with codeine #3 can also lead to dependence, addiction, or liver damage. It’s crucial always to follow your doctor’s instructions when taking any medication and to report any side effects you experience to your healthcare provider.

Codeine Promethazine Side Effects

Codeine and promethazine can cause more severe side effects, such as respiratory depression (slowed breathing), allergic reactions, or drowsiness. If you experience any of the symptoms after taking codeine and promethazine, seek medical attention right away. Codeine and promethazine are commonly used together to relieve coughs associated with respiratory tract infections or allergies. The effects of codeine and promethazine can include the following:

  • Relief of cough: Codeine is a cough suppressant that blocks the brain’s cough reflex. Promethazine is an antihistamine that can also help relieve cough by reducing inflammation in the airways.
  • Pain relief: Codeine is also a mild pain reliever that can help relieve mild-to-moderate pain.
  • Sedation: Both codeine and promethazine can cause drowsiness and sedation, which can help promote restful sleep when used at night.
  • Relaxation of muscles: Codeine and promethazine can also cause relaxation of the muscles, which can help relieve muscle spasms or tension.

The side effects of promethazine with codeine can occur to anyone, so it’s best to follow your doctor’s instructions. These medications should only be used as directed by your healthcare provider and should not be taken in more significant amounts or longer than prescribed. If you experience any codeine / promethazine side effects or have concerns about using codeine and promethazine, speak with a healthcare professional.

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What are the Side Effects of Codeine?

Constipation is one of the most common adverse effects of codeine. Most patients report some stomach discomfort and constipation following the start of codeine pharmacotherapy or increases in dose. With persistent exposure, the resolution of stomach discomfort and constipation does not occur. The clinician should recommend stool softeners along with a codeine prescription. Nausea or vomiting is another common unfavorable effect expected to subside within days to weeks of continued codeine exposure. Anti-emetic treatments in oral and rectal formulations are available to treat vomiting and nausea.

Clouded mentation or sedation following codeine treatment initiation tends to fade over time. Yet, during initiation or increasing doses, patients should acquire counseling about considering precautions at work and restrictions with driving. They should also comprehend the effects and risks of simultaneous exposure to other substances and drugs with sedating effects.

What are side effects of codeine? Other common adverse effects include the following:

  • Pruritis – Pruritus, commonly called itching, is an unpleasant sensation that causes the desire to scratch or rub the affected area.
  • Urinary Retention – Urinary retention is when a person has difficulty or cannot empty their bladder.
  • Hypersensitivity – An allergic reaction is an abnormal immune response to a normally harmless substance.
  • Bronchospasm – A condition in which the muscles around the airways in the lungs contract and narrow, making breathing difficult.
  • Tremor, blurred vision, weakness, abdominal cramps, and pancreatitis.
Educational seminar on the risks and prevention of prescription drug abuse

Clinicians must assess opioid rotation when patients chronically on a particular opioid experience intolerable adverse effects or poor relief despite dose increments. Individuals with sleep apnea or other coexisting pulmonary diseases may be at a higher risk for respiratory depression, and doses must be started and titrated cautiously.

What is codeine side effects on pregnancy? Adverse newborn outcomes such as premature birth, low birth weight, hypoxic-ischemic brain injury, and neonatal death may occur when used in pregnancy. Newborns may also have neonatal abstinence syndrome.

Short Term Effects of Codeine

Codeine is an opioid pain medication often prescribed for short-term use to manage pain. Codeine short term effects include the following:

  • Pain relief: Codeine works by binding to the spinal cord, opioid receptors in the brain, and other parts of the body, which can help to reduce pain.
  • Sedation effects on codeine: Codeine can cause drowsiness and sedation, which can help manage pain and promote rest.
  • Cough suppression: Codeine is sometimes used in cough syrup to help suppress coughing.
  • Constipation: Codeine can slow down the movement of the digestive tract, leading to constipation.
  • Nausea and vomiting: Codeine can cause nausea and vomiting, especially when taken in higher doses or for more extended periods.
  • Euphoria: Like other opioids, codeine can cause euphoria or a “high” when taken in higher doses than prescribed.
  • Respiratory depression: In high dosages or combined with other prescription drugs that depress the central nervous system, codeine can cause respiratory depression, a potentially life-threatening condition.

Long Term Effects of Codeine

Long term codeine effects, especially at high doses or in combination with other drugs, can lead to several potential adverse effects, including the following:

  • Tolerance: Over time, the body may become accustomed to the effects of codeine, leading to the need for higher doses to achieve the same level of pain relief.
  • Dependence: With prolonged use, the body may develop a physical dependence on codeine, leading to withdrawal symptoms when use is stopped.
  • Addiction: Codeine long term effects can increase the risk of developing addiction or substance use disorder, especially in individuals with a history of substance use disorders or mental health conditions.
  • Respiratory problems: Long-term use of codeine can lead to respiratory problems, including breathing difficulties, chronic cough, and even respiratory failure.
  • Liver damage: Chronic use of codeine can lead to liver damage, especially when combined with other drugs or alcohol.
  • Hormonal problems: Long-term use of codeine can lead to hormonal imbalances, including reduced testosterone levels in men and menstrual irregularities in women.
  • Cognitive impairment: Prolonged use of codeine can lead to cognitive impairment, including memory problems, slowed thinking, and difficulty concentrating.

What is the side effects of codeine on sex? Evidence suggests that long-term use of opioids like codeine can lead to sexual dysfunction, including decreased libido, erectile dysfunction, and delayed or absent orgasm. This is thought to be related to the way opioids affect the brain and the body’s natural production of hormones that are important for sexual function.

However, sexual dysfunction is not a common side effect of short-term use of codeine or other opioids. If you are experiencing sexual dysfunction and are taking codeine or another opioid, it’s critical to talk to your healthcare provider. They may be able to modify your medication plan or recommend other treatments to help alleviate your codeine sexual dysfunction symptoms. Furthermore, sexual dysfunction can have many causes, such as anxiety, depression, or other health conditions. Hence, a thorough evaluation by a healthcare provider is essential to determine the underlying cause and the best course of treatment.

Codeine Phosphate Addiction

Codeine phosphate is a powerful opioid pain medication that can be addictive when used over a long period or in high doses. The risk of codeine addiction is incredibly high when codeine is used in a way that is not prescribed by a healthcare provider, such as taking larger doses than recommended or using it for non-medical purposes.

Codeine is known to bind to opioid receptors in the brain and other parts of our body, which can lead to euphoria, relaxation, and pain relief. Over time, the body may become tolerant to the effects of codeine, requiring higher doses to achieve the same level of pain relief or to experience the desired results. This can lead to physical dependency and unwanted withdrawal symptoms when use is stopped.

The signs of codeine addiction are:

  • Using codeine in more significant amounts or for more extended periods than prescribed.
  • Craving codeine and feeling unable to control the use.
  • Continuing to use codeine despite negative consequences, such as financial or relationship problems.
  • Spending a lot of time thinking about codeine or seeking it out.
  • Using codeine to cope with emotional issues or stress.
  • Withdrawal symptoms include anxiety, agitation, sweating, and gastrointestinal problems when use is stopped.

Prescription drug addiction, such as codeine addiction, can be challenging to recognize. Codeine addiction often develops gradually and can be hidden from others. However, there are some general signs and symptoms that may indicate a prescription drug addiction, including the following:

  • Using more medication than prescribed or using it for longer than intended.
  • Continue using the medicine even after the original condition or injury has resolved.
  • Needing the drug to feel “normal” or function in daily life.
  • Experiencing withdrawal symptoms when attempting to stop or reduce medication use.
  • Continue using the medicines despite experiencing negative consequences, such as relationship problems, financial difficulties, or legal issues.
  • Spending significant time and effort obtaining the drug, such as doctor shopping or stealing from others.
  • Hiding or lying about medication use.
  • Neglecting essential responsibilities, such as work, school, or family obligations, to use the medication.
  • Using the medicine recreationally, such as crushing and snorting pills or injecting them.
  • Experiencing mood, behavior, or personality changes, such as irritability, aggression, or depression.
Support group meeting discussing recovery from codeine addiction

Codeine Addiction Treatment

If you think you or someone you’re concerned with has codeine addiction, seeking professional help is crucial. Treatment options for codeine addiction may include behavioral therapy programs like cognitive-behavioral therapy and medication-assisted treatment. These programs can help to manage withdrawal symptoms and reduce the risk of relapse.

Medication-assisted treatment (MAT) is a good treatment option for people with codeine addiction. MAT combines medication, such as buprenorphine or methadone, with behavioral therapy and counseling to address codeine addiction’s physical and psychological aspects. Buprenorphine medication is a partial opioid agonist that can aid in reducing cravings and withdrawal symptoms linked with codeine addiction. It binds to the same opioid receptors as codeine but with less euphoria and sedation. Methadone is a full opioid agonist that also works by binding to opioid receptors, but it is typically used for more severe cases of codeine addiction.

Along with medication, counseling can help address the underlying psychological factors contributing to codeine addiction. Cognitive-behavioral therapy (CBT) and contingency management (CM) are two standard behavioral therapies used in MAT. CBT helps people comprehend and change negative thought patterns and behaviors that contribute to codeine addiction, while CM rewards positive behaviors, such as staying drug-free. MAT may also be provided in a residential or inpatient setting. Working with a healthcare provider specializing in codeine addiction treatment is crucial to determine the most appropriate treatment plan.

MAT is highly effective in reducing opioid use and helps to improve the overall quality of life for individuals struggling with codeine addiction. However, it is crucial to remember that MAT is just one component of addiction treatment and that individualized, comprehensive care is essential for long-term recovery.

Detoxing from codeine addiction can be challenging, and it’s essential to seek professional help to ensure a safe and successful detox. Here are some general ways that may be involved in a codeine detox:

  • Consult with a medical professional: The first step in any detox process should be to consult a medical addiction professional, such as a doctor or addiction specialist. They can help you create a plan tailored to your needs and monitor your progress.
  • Gradual tapering: If you’ve been using codeine regularly for an extended period, abruptly stopping can lead to withdrawal symptoms. To minimize the discomfort of withdrawal, a gradual tapering schedule may be recommended, where the dosage is gradually reduced over time.
  • Medications to manage withdrawal symptoms: Your healthcare provider may prescribe medications to help manage withdrawal symptoms, such as anxiety, insomnia, and muscle aches. These may include clonidine, benzodiazepines, or antidepressants.
  • Behavioral therapy: Behavioral therapy can help address the underlying psychological and emotional factors that may have contributed to your codeine use. This may include individual therapy, group therapy, or support groups like Narcotics Anonymous.
  • Self-care: During the detox process, it’s crucial to prioritize first self-care practices such as getting enough sleep, creating a healthy diet, and engaging in exercise or other activities that promote overall well-being.

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If you or a loved one is struggling with codeine addiction or other substance use disorder(s), call for a FREE consultation 24/7 at (561) 678-0917.

Frequently Asked Questions

Here are some frequently asked questions about codeine addiction and withdrawal.

Is Codeine with Guaifenesin Addictive?

Yes, codeine with guaifenesin can be addictive. Guaifenesin is an expectorant that thins mucus, making it easier to cough up. It’s often combined with codeine in prescription cough syrups. While guaifenesin isn’t addictive, codeine is. If you find yourself craving the medication or using it more frequently than directed, talk to your healthcare provider immediately.

Is Tylenol With Codeine Addictive?

Tylenol with codeine, also known as acetaminophen with codeine, can be addictive due to the codeine in it. Codeine is an opioid that can lead to physical dependence and addiction when used long-term or in high doses. Always follow the prescribed dosage and talk to your healthcare provider if you’re concerned about addiction risk.

What is Codeine Lean?

Codeine lean, also known as purple drank or sizzurp, is a dangerous mixture of prescription cough syrup containing codeine and promethazine with soda and hard candy. It’s often abused for its euphoric and sedative effects. Drinking codeine lean can lead to respiratory depression, seizures, and even death, especially when combined with alcohol or other drugs. If you or someone you know is abusing codeine lean, seek professional help immediately.

How Long Do Opiates Stay in Your System? How Long Do Opiates Stay in Urine, Blood, & Body?

Codeine is an opioid. It is a narcotic medication commonly used for mild to moderate pain treatment, coughing, and diarrhea. Codeine binds to specific brain and spinal cord receptors, which can help reduce pain and suppress coughing and diarrhea. Like other opioids, codeine can be addictive and cause side effects such as drowsiness, constipation, and respiratory depression. It is vital to use codeine only as directed by a healthcare professional and to be aware of the risks associated with its use. The length of opioids stay in your system can vary based on several aspects, including the type of opioid, the dose taken, and individual factors such as age, weight, and metabolism.

One key difference between opiates and opioids is that opiates are all-natural compounds from the opium poppy plant. In contrast, opioids include natural and synthetic compounds that can be manufactured in a laboratory. Another critical difference is that opioids are generally considered to be more potent than opiates, meaning that they can have more substantial and long-lasting effects on the body.

Watch the video below for more information about how long opiates stay in your system.

How Long Do Opiates Stay in Your System? Video Transcript

Welcome to the We Level Up treatment center video series. In today’s video, we will discuss How Long Do Opiates Stay in Your System? How Long Do Opiates Stay in Urine, Blood, & Body? Learn the Hydrocodone, Oxycodone, & Codeine Drug Testing Facts.

The length of time that opiates remain in your system varies depending on the type of opiate, the dosage, and the frequency of use. Generally, opiates can stay in your system for two to four days. However, heavier and chronic users may have residues for up to seven days.

Opiates can be detected in the blood test for up to 24 hours and in the urine test for up to three days. Opiates can be detected in the hair follicles for up to 90 days. In chronic users, opiates can stay in the body for up to 30 days.

Opiates often have short half-lives, meaning their effects can linger for several hours even though they swiftly leave the body. However, Opioids can linger in a person’s bloodstream for several hours or days after the symptoms subside, depending on the substance used. Urine tests, one of the more common types of drug testing, can identify opioid usage for longer periods of time, often up to three to four days, and some tests can identify opioid use for up to three months.

Drugs in the opioid class are used to treat pain. Natural opioids, semi-synthetic opioids generated from natural opioids, and synthetic opioids produced in a lab are all referred to as opioids under the general term. A class of medications known as opioids contains opiates, which are organic byproducts of the poppy plant.

The main difference is that “opiate” refers to the substances derived from the opium (poppy) plant. At the same time, “opioids” are all substances that interact with opioid receptors, including those created in the lab.

What are Opioids?

Opioids, sometimes called narcotics, are medications doctors prescribe to treat persistent or severe pain. They are used by those with persistent headaches and blood alcohol levels, those recovering from surgery or dealing with excruciating pain from cancer, as well as by adults and kids who have suffered major injuries while playing sports or in falls, car accidents, or other situations.

A large class of painkillers known as opioids interact with opioid receptors in your cells to relieve pain. Opioids can be produced in a lab, such as fentanyl, or from the poppy plant. Such as morphine, Kadian, Ms. Contin, Actiq, Duragesic, etc.

Your brain cells release signals that reduce your sense of pain and increase your emotions of pleasure when opioid drugs pass through your blood and bind to opioid receptors. Opioid addiction can happen after just a week of use. The risk for long-term opioid abuse increases after only five days of taking medicine. Some individuals who only intended to use opioids for a week have continued to do so a year later.

Compared to 2019, the age-adjusted rate of drug overdose deaths rose 31% in 2020. Young individuals aged 15 to 24 saw the biggest percentage increase in fatalities, while adults aged 35 to 44 had the greatest rates of drug overdose deaths. The fight against substance use disorders and the opioid pandemic must continue in all facets.

Opiates Drugs Names

There are a variety of opiate drugs, all with different names. Some examples include codeine, morphine, oxycodone, hydrocodone, fentanyl, and methadone. It is important to know the names of opiates when seeking help for addiction, as intervention strategies and treatment plans may depend on the specific opiates being abused.

The top three opiate drugs most commonly prescribed are Hydrocodone, Oxycodone, and Codeine. Other opiate drugs may also be prescribed, depending on your needs and doctor’s advice.

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Sources

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