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Can You Take Phenibut With Adderall

Adderall With Phenibut

What is Phenibut? Nootropic drugs that can enhance cognitive function are becoming increasingly popular and available for buy on the Internet. Phenibut (â-phenyl-ã-aminobutyric acid HCl) is a neuropsychotropic drug that was discovered and introduced into clinical practice in Russia in the 1960s [1]. It has anxiolytic and nootropic (cognition enhancing) effects. It acts as a GABA-mimetic, primarily at GABAB and, to some extent, at GABAA receptors. It also stimulates dopamine receptors and antagonizes â-phenethylamine (PEA), a putative endogenous anxiogenic. The psychopharmacological activity of phenibut is similar to that of baclofen, a p-Cl-derivative of phenibut. Although the drug is not licensed in the United States, it is available through online vendors often marketed as a dietary supplement and cognitive enhancer. However, research on the prevalence and effects of phenibut use is currently limited. Taken chronically, high doses promoted tolerance to the sedative effects over time. Chronic use has also been associated with psychosis and physical dependence. Phenibut is widely used in Russia in different neurological and psychiatric disorders. In some Russian reference books, phenibut is listed as a tranquilizer, and in others as a nootropic agent. In reality, the drug appears to have both types of activity. It has been reported…