Oxycodone Withdrawal Symptoms, Timeline & Treatment

Withdrawal from oxycodone, including OxyContin, can be a challenging and uncomfortable experience for individuals who have developed a physical dependence on the drug. Oxycodone is a powerful opioid painkiller prescribed to treat moderate to severe pain.

Over time, the body can become dependent on the drug. When a person stops taking it, they can experience a range of withdrawal symptoms that can be both physical and psychological. Continue reading to learn more about this condition.


Oxycodone Withdrawal Symptoms Overview

Withdrawal from oxycodone, including OxyContin, can be a challenging and uncomfortable experience for individuals who have developed a physical dependence on the drug. Oxycodone is a powerful opioid painkiller prescribed to treat moderate to severe pain.

Over time, the body can become dependent on the drug. When a person stops taking it, they can experience a range of withdrawal symptoms that can be both physical and psychological.

Withdrawal symptoms from oxycodone can vary in intensity and duration depending on several factors, such as the duration and intensity of use, individual differences in metabolism and genetics, and other factors, such as co-occurring medical or mental health conditions.

The oxycodone withdrawal timeline can also vary depending on these factors. Still, acute withdrawal symptoms generally begin within 8-12 hours of the last dose and can last up to a week. However, some people may experience protracted withdrawal symptoms lasting several weeks or months.

OxyContin withdrawal symptoms can be similar to other opioid drugs, including heroin and morphine. Physical symptoms may include muscle aches, sweating, nausea, vomiting, diarrhea, fever, and chills. Psychological symptoms may include anxiety, depression, irritability, restlessness, and insomnia.

The severity of withdrawal symptoms of oxycodone can be distressing for individuals, and in some cases, it can lead to relapse if they attempt to quit on their own. Therefore, it’s crucial for individuals who want to quit oxycodone to seek professional help and support.

The best way to withdraw from oxycodone is under the guidance of a healthcare professional who can monitor symptoms, manage discomfort, and reduce the risk of complications. In short, oxycontin withdrawal symptoms and withdrawal from oxycodone can be challenging. Still, individuals can safely and effectively overcome their dependence on the drug with the right support and treatment.

Are Oxycontin Withdrawal Symptoms Very Dangerous?

When people use OxyContin over an extended period of time, they can develop a physical dependence on the drug, which means their body has adapted to the presence of the drug and needs it to function normally. When they stop using it, they may experience mild to severe withdrawal symptoms, which can be uncomfortable and distressing.

While OxyContin withdrawal symptoms can be challenging to manage, they are typically not life-threatening. However, some symptoms, such as muscle aches, nausea, vomiting, and diarrhea, can be uncomfortable and painful. Additionally, people undergoing OxyContin withdrawal may experience psychological symptoms such as anxiety, depression, and insomnia.

In rare cases, withdrawal from opioids like OxyContin can cause serious complications, especially if the person has a pre-existing medical condition or has been using the drug in high doses or for a long time. For example, withdrawal can lead to dehydration, electrolyte imbalances, seizures, or even respiratory failure in some cases.

It’s worth noting that the severity of withdrawal symptoms can vary widely depending on several factors, including the duration and intensity of use, individual differences in metabolism and genetics, and other factors such as the presence of co-occurring medical or mental health conditions.

It’s important to seek professional help when quitting OxyContin or any other opioid drug, as medical supervision can help manage symptoms and reduce the risk of complications. In short, while OxyContin withdrawal symptoms can be uncomfortable and challenging to manage, they are generally not considered very dangerous, especially when managed under the care of a healthcare professional.

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  1. How Long Does Oxycodone Withdrawal Last?

    How Long Does It Take To Withdraw From Oxycontin? The duration of oxycodone withdrawal can vary depending on various factors, including the individual’s physical and psychological health, the dosage and duration of oxycodone use, and the method of discontinuation. Generally, acute oxycodone withdrawal symptoms may begin within 8-12 hours of the last dose and can last up to a week. However, some people may experience protracted withdrawal symptoms lasting several weeks or months.

  2. What is The Best Way To Withdraw From Oxycodone?

    Under the guidance of a healthcare professional, the safest and most effective way to withdraw from oxycodone is through medical detoxification, which involves gradual tapering of the drug to minimize withdrawal symptoms and reduce the risk of complications. A healthcare provider may also prescribe medications to manage specific symptoms.

  3. Can You Die From Oxycontin Withdrawal or Oxycodone Withdrawals?

    Can Oxycodone Withdrawal Kill You? In general, OxyContin withdrawal itself is not directly life-threatening. However, severe withdrawal symptoms such as dehydration, electrolyte imbalances, and seizures can occur and potentially lead to life-threatening complications. Additionally, the risk of relapse and overdose increases during the period of withdrawal as individuals may try to alleviate their symptoms with drug use. Therefore, seeking professional medical help to manage OxyContin withdrawal and reduce the risk of complications is important.

Oxycodone Factsheet

Oxycodone Overview

Oxycodone is a potent opioid painkiller that can lead to physical dependence with prolonged use. Symptoms of oxycodone withdrawal, such as muscle aches, nausea, anxiety, and insomnia, can occur when individuals stop taking the drug.

The duration of oxycodone withdrawal can vary, but generally, acute symptoms can last up to a week, and protracted symptoms can last for several weeks or months. Seeking professional help to manage withdrawal symptoms and prevent complications is essential.

Medical detoxification is often recommended as the safest way to withdraw from oxycodone. In short, it’s crucial to know the potential symptoms of oxycodone withdrawal and seek professional help.


How Long Is Oxycodone Withdrawal?

The duration of oxycodone withdrawal can vary depending on several factors, including the duration and intensity of oxycodone use, the individual’s overall health, and co-occurring medical or mental health conditions.

Generally, acute symptoms can last up to a week, and protracted symptoms can last for several weeks or even months.

However, the oxycontin withdrawal symptoms duration can vary for each person. Seeking professional medical help to manage withdrawal symptoms and prevent complications is recommended.

Symptoms Of Withdrawal From Oxycodone

Withdrawal symptoms oxycodone can include both physical and psychological symptoms. Some of the physical symptoms can include:

  • Muscle aches.
  • Sweating.
  • Nausea.
  • Vomiting.
  • Diarrhea.
  • Dilated pupils.
  • Rapid heartbeat.
  • Runny nose and sneezing.
  • Tremors or shaking.
  • Fever or chills.
  • Insomnia or other sleep disturbances.

Some of the psychological symptoms can include:

  • Anxiety.
  • Depression.
  • Irritability.
  • Restlessness.
  • Cravings for oxycodone.
  • Difficulty concentrating or thinking clearly.
  • Fatigue or lack of energy.

The severity of withdrawal symptoms of oxycontin can vary depending on several factors, including the duration and intensity of oxycodone use, the individual’s overall health, and co-occurring medical or mental health conditions.

Seeking professional medical help to manage withdrawal symptoms and prevent complications is recommended.

Prescription Drug Abuse Statistics

Prescription drug abuse is a growing public health problem affecting millions of Americans yearly. According to the National Institute on Drug Abuse (NIDA), approximately 18 million people in the United States misused prescription medications in 2019. This includes opioids, benzodiazepines, stimulants, and other prescription drugs. Prescription drug abuse can lead to dependence, addiction, overdose, and even death. Understanding the scope of the problem can help policymakers, healthcare providers, and individuals take steps to prevent and address prescription drug abuse.


Approximately 70% of all drug overdose deaths in the United States in 2019 involved prescription or illicit opioids.

Source: CDC

In 2019, 9.7 million people aged 12 or older misused prescription pain relievers in the past year.

Source: NSDUH

In 2020, more than 4.6 million Americans misused prescription stimulants..

Source: DEA


What Are The Withdrawal Symptoms Of Oxycodone?

The duration of oxycodone withdrawal can vary depending on various factors, including the individual's physical and psychological health, the dosage and duration of oxycodone use, and the method of discontinuation.
The duration of oxycodone withdrawal can vary depending on various factors, including the individual’s physical and psychological health, the dosage and duration of oxycodone use, and the method of discontinuation.

Can You Have Withdrawals From Oxycodone?

Oxycodone is a potent opioid painkiller that can lead to physical dependence with prolonged use. When individuals who have developed dependence stop taking the drug, they can experience withdrawal symptoms. Withdrawal from oxycodone can be challenging and uncomfortable, both physically and emotionally. Some individuals may hesitate to stop taking the drug due to the fear of experiencing withdrawal symptoms.

The onset and duration of withdrawal symptoms from oxycodone can vary depending on several factors, including the duration and intensity of oxycodone use, the individual’s overall health, and co-occurring medical or mental health conditions. The oxycontin withdrawal timeline can differ for everyone, but acute symptoms generally last up to a week, and protracted symptoms can last for several weeks or even months.

Withdrawal symptoms from oxycodone can be both physical and psychological. Some physical symptoms can include muscle aches, sweating, nausea, vomiting, diarrhea, dilated pupils, rapid heartbeat, runny nose and sneezing, tremors or shaking, fever or chills, insomnia, or other sleep disturbances.

Psychological symptoms can include anxiety, depression, irritability, restlessness, cravings for oxycodone, difficulty concentrating or thinking clearly, and fatigue or lack of energy. Some individuals may also experience other symptoms, such as loss of appetite, mood swings, and a weakened immune system.

Oxycontin withdrawal tips may include seeking professional medical help to manage withdrawal symptoms and prevent complications. Medical detoxification is often recommended as the safest way to withdraw from oxycodone. Medical professionals may use medications to help manage withdrawal symptoms, such as methadone, buprenorphine, or clonidine. Therapy, support groups, and other resources can also help individuals manage the psychological symptoms of oxycodone withdrawal.

What does oxycontin withdrawal feel like? The experience of oxycontin withdrawal can vary depending on the individual and the severity of their dependence. Some individuals may describe feeling flu-like symptoms, while others may experience intense cravings for the drug. The experience of oxycontin withdrawal can be uncomfortable, but it is important to remember that the symptoms are temporary and can be managed with professional help.

In summary, withdrawals from oxycodone can be challenging and uncomfortable, both physically and emotionally. Seeking professional medical help to manage withdrawal symptoms and prevent complications is recommended. It’s important to remember that the symptoms are temporary and can be managed with the right treatment and support.

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How Long Does It Take To Withdraw From Oxycodone?

Oxycodone is a potent opioid painkiller that can cause physical dependence with prolonged use. When individuals who have developed dependence stop taking the drug, they can experience withdrawal symptoms. The duration of oxycodone withdrawal can vary depending on several factors, including the duration and intensity of oxycodone use, the individual’s overall health, and co-occurring medical or mental health conditions.

The oxycontin withdrawal symptoms timeline can differ for everyone, but acute symptoms can generally last up to a week, and protracted symptoms can last for several weeks or even months. The severity of symptoms can also vary depending on the individual and their level of dependence. For example, someone who has been taking 30 mg of oxycodone daily for several months may experience more severe withdrawal symptoms than someone who has been taking a lower dose for a shorter period.

The first symptoms of oxycontin withdrawal can occur within 6 to 12 hours of the last dose and peak within 1 to 3 days. The severity and duration of symptoms can vary. Still, common symptoms can include muscle aches, sweating, nausea, vomiting, diarrhea, dilated pupils, rapid heartbeat, runny nose and sneezing, tremors or shaking, fever or chills, insomnia or other sleep disturbances, anxiety, depression, irritability, restlessness, cravings for oxycodone, difficulty concentrating or thinking clearly, and fatigue or lack of energy.

How Long Does Oxycontin Withdrawal Last?

It’s important to note that the duration of oxycontin withdrawal can be influenced by several factors, including the withdrawal method, the severity of dependence, and the presence of co-occurring medical or mental health conditions. For example, individuals who quit “cold turkey” may experience more severe symptoms than those who gradually taper their dose under medical supervision.

In general, oxycontin withdrawal can last for several weeks or even months. Protracted symptoms can include anxiety, depression, insomnia, and cravings for the drug. However, the duration of withdrawal symptoms can be managed with professional help. Medical detoxification is often recommended as the safest way to withdraw from oxycodone, and medical professionals may use medications to help manage withdrawal symptoms, such as methadone, buprenorphine, or clonidine.

In conclusion, the duration of oxycodone withdrawal can vary depending on several factors, including the severity of dependence, the method of withdrawal, and the presence of co-occurring medical or mental health conditions. Generally, the oxycontin withdrawal symptoms timeline can last up to a week for acute symptoms and several weeks or months for protracted symptoms. Professional medical help and support are recommended to manage withdrawal symptoms and prevent complications.

How Long Does Withdrawal Symptoms Last From Oxycontin? 30 Mg Oxycodone Withdrawal

It’s worth noting that the duration of oxycontin withdrawal symptoms can also depend on the dose of oxycodone. For example, someone taking a high dose of 30 mg of oxycodone may experience more severe withdrawal symptoms and a longer withdrawal duration than someone taking a lower dose.

The length of oxycodone withdrawal can vary depending on several factors, including the withdrawal method, dependence severity, and co-occurring medical or mental health conditions. Seeking professional medical help and support is recommended to manage withdrawal symptoms, including using medications such as methadone, buprenorphine, or clonidine, which can help ease the symptoms and prevent complications.

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How Long Do Withdrawal Symptoms Last From Oxycontin?

The duration of withdrawal symptoms from Oxycontin, or oxycodone, can vary depending on several factors. Acute symptoms typically last about a week, while protracted symptoms persist for several weeks or months. However, the exact duration of withdrawal symptoms can depend on several factors, such as the intensity and duration of Oxycontin use, the individual’s overall health, and the presence of co-occurring medical or mental health conditions.

During the acute phase of Oxycontin withdrawal, individuals may experience various physical and psychological symptoms. Physical symptoms may include muscle aches, sweating, nausea, vomiting, diarrhea, dilated pupils, rapid heartbeat, runny nose, sneezing, tremors or shaking, fever, or chills. Psychological symptoms may include anxiety, depression, irritability, restlessness, cravings for oxycodone, difficulty concentrating or thinking clearly, and fatigue or lack of energy.

The duration of withdrawal symptoms from Oxycontin, or oxycodone, can vary depending on several factors.
The duration of withdrawal symptoms from Oxycontin, or oxycodone, can vary depending on several factors.

In the protracted phase, individuals may experience symptoms such as insomnia or other sleep disturbances, anxiety, depression, irritability, restlessness, and cravings for Oxycontin. The severity and duration of these symptoms can vary based on individual factors, including the length and intensity of Oxycontin use.

It’s important to note that the duration of Oxycontin withdrawal symptoms can be influenced by several factors, such as the method of withdrawal and the presence of co-occurring medical or mental health conditions. Abruptly stopping Oxycontin use “cold turkey” can result in more severe and longer-lasting withdrawal symptoms than those who gradually taper their dose under medical supervision. Additionally, co-occurring mental health conditions such as depression or anxiety may prolong the duration of withdrawal.

Overall, the duration of Oxycontin withdrawal symptoms can vary from person to person and depends on several factors. Seeking professional medical help and support is recommended to manage withdrawal symptoms, including using medications such as methadone, buprenorphine, or clonidine, which can help ease the symptoms and prevent complications.

Can You Die From Oxycodone Withdrawal? Oxycodone Withdrawal Treatment

The treatment for oxycodone withdrawal typically involves a combination of medication-assisted therapy, behavioral therapy, and support groups. Medications such as methadone, buprenorphine, or clonidine may be used to manage withdrawal symptoms, while behavioral therapy can help address underlying issues related to substance abuse.

Support groups like Narcotics Anonymous can provide ongoing support and accountability throughout recovery. It’s important to seek professional medical help and support for oxycodone withdrawal to ensure a safe and successful recovery.

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Oxycodone Withdrawal We Level Up Dual Diagnosis Treatment

The definition of dual diagnosis (also referred to as co-occurring disorders) can differ between institutions. However, it is generally described as the specific treatment of someone diagnosed with a substance use disorder and a mental health disorder simultaneously. Treating dual-diagnosis clients is a critical aspect of our inpatient treatment experience because co-occurring disorders are strongly correlated with instances of substance abuse.

Creating a treatment plan that addresses the physical aspects of withdrawal, the psychological connection with drug use, and managing underlying mental health disorders is part of setting clients up for success.  A thorough mental health analysis identifies possibilities for treatment.  Meeting with mental health counselors and medical care providers means access to behavioral therapy and medication treatment. At our dual diagnosis treatment center, We Level Up can implement the highest quality of care. 

We recognize the fragile complexities of how mental and substance abuse disorders can influence others and sometimes result in a vicious cycle of addiction.  That’s why we offer specialized treatment in dual-diagnosis cases to provide the most excellent chance of true healing and long-lasting recovery.

Accepting that you may be living with a mental illness can be challenging. However, treating the presenting substance abuse case can be magnitudes easier once properly diagnosed and treated. Only a properly trained medical professional can diagnose these underlying conditions.  If you believe you are suffering from a disorder alongside addiction, we urge you to seek a qualified treatment center to begin your journey to recovery. Call We Level Up today.

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Sources
  1. National Institute on Drug Abuse – https://www.drugabuse.gov/drug-topics/opioids/opioid-overdose-crisis
  2. Substance Abuse and Mental Health Services Administration – https://www.samhsa.gov/
  3. Centers for Disease Control and Prevention – https://www.cdc.gov/drugoverdose/index.html
  4. National Institutes of Health – https://www.nih.gov/
  5. Food and Drug Administration – https://www.fda.gov/drugs/information-drug-class/opioid-medications
  6. Department of Health and Human Services – https://www.hhs.gov/
  7. National Council for Behavioral Health – https://www.thenationalcouncil.org/topics/substance-use-disorders/
  8. Office of National Drug Control Policy – https://www.whitehouse.gov/ondcp/
  9. U.S. Department of Justice – https://www.justice.gov/
  10. U.S. Department of Veterans Affairs – https://www.mentalhealth.va.gov/opioid-safety/